Bio Protocol is the first cross-chain platform focused on decentralized science (DeSci), aimed at revolutionizing research funding and intellectual property management through blockchain technology. The platform organizes a global community by creating BioDAO to fund, develop, and govern tokenized scientific intellectual property.
The native token BIO is used for ecosystem incentives and governance. The total supply is 3,320,000,000 coins, with allocations including ecosystem incentives (25%), core contributors (21.2%), community auctions (20%), investors and advisors (17.8%), and liquidity and reserves (15%).

Bio Protocol Project Overview
Bio Protocol has built a multi-chain interoperability architecture connecting Ethereum, Solana, and Base, and has Uniswap and integrate with decentralized exchanges like CoW Swap to ensure liquidity.
The platform supports the creation of BioDAOs in specific fields (such as VitaDAO, AthenaDAO), focusing on longevity, women’s health, synthetic biology, and other areas. Its core features include the introduction of BioAgents—AI tools for hypothesis generation, experimental design, and knowledge graph construction, with all data stored in RDF triplet format and evaluated on-chain through JudgeLLM.
BIO Current Market Conditions and Recent Performance
As of September 4, 2025, according to data from exchanges like Gate, the price of the BIO token has experienced significant fluctuations over the past period. Its historical highest price was $0.9226, set in January 2025, while its historical lowest price was $0.04074 in April 2025.
Recently, BIO has shown strong momentum. In August 2025, BIO reached a six-month high of $0.1514, then consolidated around $0.138. This recovery is attributed to its first major biotechnology project funded—a $80,000 clinical trial for brain health, as well as its collaboration with Cerebrum DAO.
From a technical perspective, BIO has recently cleared multiple key resistance levels, breaking through the 7-day simple moving average of $0.116 and the 23.6% Fibonacci retracement level of $0.128. Trading activity has also surged dramatically, with daily trading volume soaring over 700%, exceeding $440 million, indicating improved market depth and investor interest.
Key factors influencing BIO price
The price of BIO is driven by various factors:
Adoption Rate and Ecological Development: More DAOs tokenizing intellectual property on the platform will increase the use cases and demand for BIO. For example, BioDAO has made an investment of 24.3 million dollars.
Staking Activity: The number of BIO tokens staked has risen to over 125 million, accounting for approximately 3.5% of the circulating supply. This reduces the market circulation, which may amplify price effects when demand increases.
Technology Development and Collaboration: Key updates for 2025 include multi-chain expansion, AI agent integration, and liquidity engine optimization. Collaborations with renowned institutions (such as Binance Labs) also provide credibility.
Market Sentiment and Macroeconomic Environment: Broader cryptocurrency market cycles, Bitcoin halving events, and macroeconomic factors such as inflation can all impact the price of BIO.
Token Unlocking: Approximately 1.6 million coins are unlocked daily, which may bring some selling pressure and is a potential risk factor.
BIO coin price prediction 2025
For 2025, analysts have provided different forecast ranges:
Short-term outlook: Technical analysis shows that if BIO can break through the resistance level of $0.145, it may further rise towards the $0.16 - $0.17 range. Some harmonic pattern analyses even indicate that the upward target could be close to $0.1800.
Overall Year Outlook: Based on predictions from multiple sources, the potential low for BIO in 2025 may be around $0.12, while the potential high could reach $0.28, with an average annual price expected to be around $0.20. There are also forecasts indicating that if market sentiment is optimistic, it could peak at $0.50.
BIO Price Prediction 2026-2030
In the medium to long term, as the DeSci field matures and the Bio Protocol ecosystem expands, the price of BIO is expected to grow. Below is a comprehensive table based on multiple forecasts:
| year | Potential Low ($) | Potential Average Value ($) | Potential High ($) |
|---|---|---|---|
| 2026 | 0.18 | 0.28 | 0.40 |
| 2027 | 0.25 | 0.36 | 0.50 |
| 2028 | 0.32 | 0.45 | 0.60 |
| 2029 | 0.40 | 0.55 | 0.70 |
| 2030 | 0.50 | 0.65 | 0.80 |
It is important to note that there are also other predictive models that provide different values. For example, some conservative forecasts suggest that the average price may be around $1.58 in 2030, while some very optimistic predictions even see the potential for $3.00 under certain conditions. This fully illustrates the uncertainty of cryptocurrency market predictions.
The risks and opportunities of investing in BIO
opportunity
Track Potential: DeSci is an emerging and disruptive track, and Bio Protocol, as an early participant, is expected to capture the industry’s growth dividends.
Practical application support: The project has started funding real biotechnology clinical trials (such as Percepta) and can generate potential royalty income through tokens like CLAW, providing support for its token value that differs from purely speculative coins.
Deflationary mechanism: Staking activities lock up a large number of circulating coins, reducing market supply, which may have a positive impact on prices.
Strong backing: Received investment and support from well-known institutions such as Binance Labs, increasing the credibility of the project.
risk
Market Volatility: The cryptocurrency market is known for its high volatility, and BIO is no exception. Macroeconomic environment, changes in regulatory policies, or Bitcoin price Severe fluctuations can significantly affect the price of BIO.
Token Unlocking: Tokens held by the team, investors, and advisors will gradually unlock into the market (approximately 1.6 million coins per day), which may create sustained selling pressure.
Competitive Pressure: The DeSci field may encounter other strong competitors, dividing the market and user attention.
Technical and Development Risks: The execution of the project roadmap, the progress of technological development, and the expansion of the ecosystem may face challenges, and failure to meet expectations may affect investor confidence.
Conclusion
Overall, Bio Protocol (BIO) plays the role of an innovator in the DeSci field, and its unique value proposition and initial ecological development provide room for imagination regarding its future price. The combination of technical indicators and fundamentals outlines a cautiously optimistic picture for its medium to long-term prospects.
However, cryptocurrency investments are inherently associated with high risks. The price of BIO may still experience significant fluctuations in the short term. Investors must conduct thorough research (DYOR) before making decisions, gain a deep understanding of the project details, assess their own risk tolerance, and consider diversifying their investments to reduce risk.
Future Price trend It will largely depend on the actual adoption of the Bio Protocol ecosystem, the achievement of technical milestones, and the broader cryptocurrency market cycle.